Code: EU14651
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Description Tvaptan 30 mg Centurion Laboratories
Specification Tvaptan 30 mg Centurion Laboratories
Features
Active substance
Tolvaptan
Also known as
OPC-41061
Blood pressure
Generally has minimal effect on blood pressure
Chemical name
N-[4-[(5R)-7-chloro-5-hydroxy-2-oxo-3-oxabicyclo[4.3.0]nona-1,6-dien-9-yl]pentyl]-1-methylbenzimidazole-2-carboxamide
Dosage (medical)
Initial dose of 15 mg once daily, may be increased to a maximum of 60 mg daily based on serum sodium levels and clinical response
Dosage (sports)
Not applicable as it is not typically used in sports
Effects
Increases urine output without affecting the excretion of potassium and sodium, corrects hyponatremia
Formula
C_26H_25ClN_2O_3
Half-life
Approximately 12 hours
Hepatotoxicity
Can cause significant increases in liver enzymes, potential for serious liver injury
Lab Test
Monitoring of serum sodium levels and liver function tests are necessary
Main action
Vasopressin V2 receptor antagonist
Side effects
Thirst, dry mouth, nausea, polyuria, hyperglycemia, raised liver enzymes
Storage conditions
Store at room temperature away from moisture and heat
Strength
30mg
Substance class
Benzazepine derivative
Trade name
Samsca
Use in sports
None, as it is not known to enhance athletic performance
Water Retention
Reduces water retention by promoting free water excretion
Manufacturer
Centaur Pharmaceuticals Pvt. Ltd
Packing
4 tabs/blister
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